Experienced Exporter of 2, 2

Overview

Basic Info.

Colour	White
Melting Point	92-96ºC
Content	Greater Than or Equal to 99%
Molecular Weight	144.13
Transport Package	Barrel or Bag
Specification	25Kg/Barrel or as required
Trademark	Juyuan
Origin	Xinxiang, Henan
Production Capacity	200 Tons/Month

Product Description

Brief Introduction

Brief Introduction
Name	Meldrum's Acid
Synonyms	2,2-Dimethyl-1,3-Dioxane-4,6-Dione
	Isopropylidene Malonate
	Malonic Acid Cyclic Isopropylidene Ester
	Cyclic Isopropylidene Malonate
CAS	2033-24-1
EINECS	217-992-8
Molecular Formula	C6H8O4
Molecular weight	144.13
Pureness	≥99%
Production Capacity	200 tons/month

Properties

Properties
Density	1.1311 (rough estimate)
Melting Point	92-96°C(lit.)
Boling Point	182.71°C (rough estimate)
Flash Point	150.1°C
Water Solubility	2.5 g/100 mL (20 ºC)
Vapor Presure	0.044-133Pa at 25ºC
Appearance	White crystalline powder
Merck	145817
BRN	117310
pKa	5.1(at 25ºC)
Storage Condition	2-8°C
Refractive Index	1.4434 (estimate)
MDL	MFCD00006638
InChI	InChI=1S/C6H8O4/c1-6(2)9-4(7)3-5(8)10-6/h3H2,1-2H3
InChIKey	GXHFUVWIGNLZSC-UHFFFAOYSA-N

Product Description

Product Description
Due to its unique structure and the vast array of substituents that can be attached to its core, Meldrum's acid is a molecule with exceptional chemical properties. In water, it has a remarkably low pKa value of about 4.9. Its C5 position is readily involved in electrophilic substitution reactions whereas the C4 and C6 positions are easily attacked by nucleophiles. At elevated temperatures Meldrum's acid undergoes distinctive decomposition pathways, which can be used in cycloaddition and acylation reactions.
Solubility
Meldrum's acid or 2,2-dimethyl-1,3-dioxane-4,6-dione is an organic compound with formula . Its molecule has a heterocyclic core with four carbon and two oxygen atoms; the formula can also be written as [−O− (C (CH3)2)−O− (C=O)− (CH2)− (C=O)−] . It is a crystalline colorless solid, sparingly soluble in water. It decomposes on heating with release of carbon dioxide and acetone.
Stability

1. It will not decompose if used and stored according to specifications. No known hazard reactions. Avoid oxides, moisture/moisture.
2. It's very stable and can be stored for a long time at room temperature.

Storage Attentions
Keep the storage device sealed and stored in a cool, dry place. Ensure that the workshop is well ventilated or vented.

Application

Application

1. It's used as a pharmaceutical intermediate. The ring (sub) isopropyl malonate can be used as an intermediate in pharmaceutical synthesis, and it can be used to prepare the compound 3-oxo-4-phenylvalerate Ethyl, further preparation of 3, 4-disubstituted-6-phenylethylpyridinone HIV-1 reverse transcriptase inhibitors.2. It's used in organic synthesis.The protective reagent is obtained by aldol condensation and reduction with triethylamine formaldehyde. the benzyl substituted michele acid is hydrolyzed, lost CO2 and chlorosulfonic acid for Friedel-Crafts cyclization to produce 2, 3-dihydro-2-indanone. Accelerate the Noven Gall concentration reaction between aldehyde and Michaelis acid in ionic liquid (Knoevenagel condensations).

Packaging & Transport

Packaging & Transport

Payment

Payment

Company Profile

Company profile

Xinxiang Juyuan Biological Technology Co., Ltd. is specialized in the manufacture, research and development of pharmaceutical intermediates and fine chemicals, such as Biapenem, and series intermediates of Penem.
The company is located in the economic development zone in Xinxiang City, Henan Province, enjoying a superior location and convenient transportation.The company is armed with top-notch technicians, advanced production equipments and testing instruments as well as perfect Q.C. system. Products are sold not only around China, but also to Europe and the US as well as the Asia-Pacific Region.Upholding the Strategic Policy of "Survive through Quality, Develop through Technology", we sincerely welcome the cooperation of friends from all walks of life for a bright future.

FAQ

FAQ:
Q1:Will you supply samples for testing?
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.
Q2:What's your MOQ?
A: Our MOQ starts from 1kg.
Q3:Which kind of payment terms do you accept?
A: Payment by LC, T/T, D/P, PayPal, Western Union, Small-amount payment
Q4:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
Q5. Are you manufacturer or trade company?We are a comprehensive technology enterprise that focuses on the production and research and development of intermediates and fine chemicals.
Q6:How to contact us?You can choose your interested products and send inquiry to us.You can dial our telephone directly, you will get our reply.